W9C (p.Trp9Cys) variant of TIGIT (Q495A1)
W9C (p.Trp9Cys) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
W9C (p.Trp9Cys) variant details
- p.Trp9Cys
- gnomAD 3-114294088-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.615
- REVEL 0.57
- MetaLR 0.38
- MetaSVM -0.27
- CADD 28.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available