W3L (p.Trp3Leu) variant of TIGIT (Q495A1)
W3L (p.Trp3Leu) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
W3L (p.Trp3Leu) variant details
- p.Trp3Leu
- gnomAD 3-114294069-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.24
- MetaLR 0.19
- MetaSVM -0.83
- CADD 23.30
- PolyPhen-2 0.46
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available