T24S (p.Thr24Ser) variant of TIGIT (Q495A1)
T24S (p.Thr24Ser) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
T24S (p.Thr24Ser) variant details
- p.Thr24Ser
- rs866543667
- gnomAD 3-114293910-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0836
- CADD 2.38
- SIFT 0.53
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available