S40S (p.Ser40Ser) variant of TIGIT (Q495A1)
S40S (p.Ser40Ser) in TIGIT (Q495A1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
S40S (p.Ser40Ser) variant details
- p.Ser40Ser
- gnomAD 3-114293980-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.184
- CADD 5.52
- Most common in the Non-Finnish European population (allele frequency 1.4e-06)
- Structural context available
- Literature evidence available