S40F (p.Ser40Phe) variant of TIGIT (Q495A1)
S40F (p.Ser40Phe) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
S40F (p.Ser40Phe) variant details
- p.Ser40Phe
- gnomAD rs1474404755
- Missense
- Variant Prioritization Score for Impact Estimate 0.646
- REVEL 0.63
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available