S34P (p.Ser34Pro) variant of TIGIT (Q495A1)
S34P (p.Ser34Pro) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
S34P (p.Ser34Pro) variant details
- p.Ser34Pro
- rs1200542845
- gnomAD 3-114293966-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- CADD 2.91
- SIFT 0.97
- Most common in the South Asian population (allele frequency 7.3e-05)
- Structural context available
- Literature evidence available