S20T (p.Ser20Thr) variant of TIGIT (Q495A1)
S20T (p.Ser20Thr) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
S20T (p.Ser20Thr) variant details
- p.Ser20Thr
- gnomAD 3-114294119-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.02
- MetaLR 0.07
- MetaSVM -1.03
- CADD 10.10
- PolyPhen-2 0.02
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available