S20P (p.Ser20Pro) variant of TIGIT (Q495A1)
S20P (p.Ser20Pro) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
S20P (p.Ser20Pro) variant details
- p.Ser20Pro
- gnomAD 3-114294119-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.16
- MetaLR 0.09
- MetaSVM -1.02
- CADD 18.30
- PolyPhen-2 0.48
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available