S20L (p.Ser20Leu) variant of TIGIT (Q495A1)
S20L (p.Ser20Leu) in TIGIT (Q495A1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
S20L (p.Ser20Leu) variant details
- p.Ser20Leu
- rs1322095400
- gnomAD 3-114294116-G-GC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.224
- CADD 20.20
- Population evidence available
- Structural context available
- Literature evidence available