S20A (p.Ser20Ala) variant of TIGIT (Q495A1)
S20A (p.Ser20Ala) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
S20A (p.Ser20Ala) variant details
- p.Ser20Ala
- gnomAD 3-114294119-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.02
- MetaLR 0.06
- MetaSVM -1.04
- CADD 10.80
- PolyPhen-2 0.01
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available