R14W (p.Arg14Trp) variant of TIGIT (Q495A1)
R14W (p.Arg14Trp) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
R14W (p.Arg14Trp) variant details
- p.Arg14Trp
- gnomAD 3-114294101-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.16
- MetaLR 0.13
- MetaSVM -1.03
- CADD 24.50
- PolyPhen-2 0.71
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available