R14G (p.Arg14Gly) variant of TIGIT (Q495A1)
R14G (p.Arg14Gly) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R14G (p.Arg14Gly) variant details
- p.Arg14Gly
- TOPMed rs2078438130
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.04
- CADD 22.00
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available