Q15P (p.Gln15Pro) variant of TIGIT (Q495A1)
Q15P (p.Gln15Pro) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Q15P (p.Gln15Pro) variant details
- p.Gln15Pro
- gnomAD rs1481730480
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.27
- CADD 24.20
- PolyPhen-2 0.91
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available