Q15L (p.Gln15Leu) variant of TIGIT (Q495A1)
Q15L (p.Gln15Leu) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
Q15L (p.Gln15Leu) variant details
- p.Gln15Leu
- gnomAD 3-114294105-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.22
- MetaLR 0.15
- MetaSVM -0.95
- CADD 23.10
- PolyPhen-2 0.81
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 4.6e-06)
- Structural context available
- Literature evidence available