Q11P (p.Gln11Pro) variant of TIGIT (Q495A1)
Q11P (p.Gln11Pro) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
Q11P (p.Gln11Pro) variant details
- p.Gln11Pro
- TOPMed rs894398089
- gnomAD rs894398089
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.24
- CADD 24.10
- PolyPhen-2 0.95
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available