Q11* (p.Gln11Ter) variant of TIGIT (Q495A1)
Q11* (p.Gln11Ter) in TIGIT (Q495A1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
Q11* (p.Gln11Ter) variant details
- p.Gln11Ter
- rs981665642
- gnomAD 3-114293888-C-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.223
- CADD 5.34
- Most common in the African/African-American population (allele frequency 6.3e-05)
- Structural context available
- Literature evidence available