P17L (p.Pro17Leu) variant of TIGIT (Q495A1)
P17L (p.Pro17Leu) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
P17L (p.Pro17Leu) variant details
- p.Pro17Leu
- gnomAD 3-114294111-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.07
- CADD 4.78
- PolyPhen-2 0.00
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available