P17A (p.Pro17Ala) variant of TIGIT (Q495A1)
P17A (p.Pro17Ala) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data, published literature, and structural context.
P17A (p.Pro17Ala) variant details
- p.Pro17Ala
- rs1352999409
- gnomAD 3-114293882-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0448
- CADD 0.20
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available