N32T (p.Asn32Thr) variant of TIGIT (Q495A1)
N32T (p.Asn32Thr) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
N32T (p.Asn32Thr) variant details
- p.Asn32Thr
- gnomAD rs1324498331
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.20
- CADD 22.80
- PolyPhen-2 1.00
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available