M1T (p.Met1Thr) variant of TIGIT (Q495A1)
M1T (p.Met1Thr) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
M1T (p.Met1Thr) variant details
- p.Met1Thr
- gnomAD 3-114293886-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- CADD 6.92
- SIFT 0.40
- Most common in the Middle Eastern population (allele frequency 0.00024)
- Structural context available
- Literature evidence available