M1L (p.Met1Leu) variant of TIGIT (Q495A1)
M1L (p.Met1Leu) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
M1L (p.Met1Leu) variant details
- p.Met1Leu
- rs1261868555
- gnomAD 3-114293885-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0742
- CADD 2.34
- SIFT 0.37
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available
- Literature evidence available