L7V (p.Leu7Val) variant of TIGIT (Q495A1)
L7V (p.Leu7Val) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
L7V (p.Leu7Val) variant details
- p.Leu7Val
- gnomAD 3-114294080-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.08
- MetaLR 0.20
- MetaSVM -0.92
- CADD 23.00
- PolyPhen-2 0.64
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available