L7P (p.Leu7Pro) variant of TIGIT (Q495A1)
L7P (p.Leu7Pro) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L7P (p.Leu7Pro) variant details
- p.Leu7Pro
- gnomAD rs1435416102
- Missense
- Variant Prioritization Score for Impact Estimate 0.513
- REVEL 0.42
- CADD 25.00
- PolyPhen-2 0.99
- SIFT 0.06
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available