L7M (p.Leu7Met) variant of TIGIT (Q495A1)
L7M (p.Leu7Met) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L7M (p.Leu7Met) variant details
- p.Leu7Met
- gnomAD 3-114294080-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.14
- MetaLR 0.29
- MetaSVM -0.83
- CADD 23.60
- PolyPhen-2 0.99
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available