L7L (p.Leu7Leu) variant of TIGIT (Q495A1)
L7L (p.Leu7Leu) in TIGIT (Q495A1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L7L (p.Leu7Leu) variant details
- p.Leu7Leu
- rs1017370946
- gnomAD 3-114294082-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.341
- CADD 13.20
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available