L6I (p.Leu6Ile) variant of TIGIT (Q495A1)
L6I (p.Leu6Ile) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L6I (p.Leu6Ile) variant details
- p.Leu6Ile
- gnomAD 3-114294077-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.06
- MetaLR 0.16
- MetaSVM -0.93
- CADD 11.20
- PolyPhen-2 0.10
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available