L5R (p.Leu5Arg) variant of TIGIT (Q495A1)
L5R (p.Leu5Arg) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
L5R (p.Leu5Arg) variant details
- p.Leu5Arg
- TOPMed rs1363645948
- gnomAD rs1363645948
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.27
- CADD 23.70
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available