L5L (p.Leu5Leu) variant of TIGIT (Q495A1)
L5L (p.Leu5Leu) in TIGIT (Q495A1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
L5L (p.Leu5Leu) variant details
- p.Leu5Leu
- gnomAD 3-114294076-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.539
- CADD 7.04
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- Literature evidence available