L18P (p.Leu18Pro) variant of TIGIT (Q495A1)
L18P (p.Leu18Pro) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
L18P (p.Leu18Pro) variant details
- p.Leu18Pro
- Ensembl rs1576134457
- Missense
- Variant Prioritization Score for Impact Estimate 0.389
- REVEL 0.37
- CADD 21.50
- PolyPhen-2 0.80
- SIFT 0.03
- Population evidence available
- Structural context available