L18H (p.Leu18His) variant of TIGIT (Q495A1)
L18H (p.Leu18His) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L18H (p.Leu18His) variant details
- p.Leu18His
- gnomAD 3-114294114-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.20
- MetaLR 0.25
- MetaSVM -0.85
- CADD 20.30
- PolyPhen-2 0.84
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available