L18F (p.Leu18Phe) variant of TIGIT (Q495A1)
L18F (p.Leu18Phe) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
L18F (p.Leu18Phe) variant details
- p.Leu18Phe
- rs1202694984
- gnomAD 3-114293942-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- CADD 3.37
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available