L13P (p.Leu13Pro) variant of TIGIT (Q495A1)
L13P (p.Leu13Pro) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
L13P (p.Leu13Pro) variant details
- p.Leu13Pro
- gnomAD 3-114294099-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.577
- REVEL 0.61
- MetaLR 0.32
- MetaSVM -0.42
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available