L13M (p.Leu13Met) variant of TIGIT (Q495A1)
L13M (p.Leu13Met) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
L13M (p.Leu13Met) variant details
- p.Leu13Met
- gnomAD 3-114294098-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.28
- MetaLR 0.30
- MetaSVM -0.77
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available