K37N (p.Lys37Asn) variant of TIGIT (Q495A1)
K37N (p.Lys37Asn) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
K37N (p.Lys37Asn) variant details
- p.Lys37Asn
- TOPMed rs2078447984
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.12
- CADD 22.60
- PolyPhen-2 0.16
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available