K37F (p.Lys37Phe) variant of TIGIT (Q495A1)
K37F (p.Lys37Phe) in TIGIT (Q495A1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
K37F (p.Lys37Phe) variant details
- p.Lys37Phe
- rs1223849992
- gnomAD 3-114293937-CCAAA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.467
- CADD 8.71
- Most common in the Latino/Admixed American population (allele frequency 8.6e-05)
- Structural context available
- Literature evidence available