I8V (p.Ile8Val) variant of TIGIT (Q495A1)
I8V (p.Ile8Val) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
I8V (p.Ile8Val) variant details
- p.Ile8Val
- ESP rs149574739
- gnomAD rs149574739
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.05
- CADD 16.50
- PolyPhen-2 0.01
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 7.4e-06)
- Structural context available