I8F (p.Ile8Phe) variant of TIGIT (Q495A1)
I8F (p.Ile8Phe) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
I8F (p.Ile8Phe) variant details
- p.Ile8Phe
- ESP rs149574739
- gnomAD rs149574739
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- REVEL 0.05
- CADD 22.30
- PolyPhen-2 0.03
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available