I42T (p.Ile42Thr) variant of TIGIT (Q495A1)
I42T (p.Ile42Thr) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
I42T (p.Ile42Thr) variant details
- p.Ile42Thr
- gnomAD 3-114295608-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.19
- MetaLR 0.03
- MetaSVM -1.00
- CADD 13.40
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available