I41V (p.Ile41Val) variant of TIGIT (Q495A1)
I41V (p.Ile41Val) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
I41V (p.Ile41Val) variant details
- p.Ile41Val
- gnomAD rs1192629675
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.12
- CADD 11.20
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available