I33V (p.Ile33Val) variant of TIGIT (Q495A1)
I33V (p.Ile33Val) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
I33V (p.Ile33Val) variant details
- p.Ile33Val
- rs13098836
- cosmic curated COSV10530
- UniProt VAR 056079
- 1000Genomes rs13098836
- Missense
- Variant Prioritization Score for Impact Estimate 0.0605
- REVEL 0.05
- CADD 1.97
- PolyPhen-2 0.01
- SIFT 0.34
- Most common in the HGDP:SAN population (allele frequency 0.083)
- Structural context available