I27V (p.Ile27Val) variant of TIGIT (Q495A1)
I27V (p.Ile27Val) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
I27V (p.Ile27Val) variant details
- p.Ile27Val
- ExAC rs775439016
- gnomAD rs775439016
- Missense
- Variant Prioritization Score for Impact Estimate 0.0356
- REVEL 0.01
- CADD 1.82
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available