G39D (p.Gly39Asp) variant of TIGIT (Q495A1)
G39D (p.Gly39Asp) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G39D (p.Gly39Asp) variant details
- p.Gly39Asp
- TOPMed rs1428691057
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.09
- CADD 17.00
- PolyPhen-2 0.05
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available