G39C (p.Gly39Cys) variant of TIGIT (Q495A1)
G39C (p.Gly39Cys) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
G39C (p.Gly39Cys) variant details
- p.Gly39Cys
- gnomAD 3-114295598-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.27
- MetaLR 0.22
- MetaSVM -0.69
- CADD 23.70
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available