G38D (p.Gly38Asp) variant of TIGIT (Q495A1)
G38D (p.Gly38Asp) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
G38D (p.Gly38Asp) variant details
- p.Gly38Asp
- Ensembl rs752473184
- Missense
- Variant Prioritization Score for Impact Estimate 0.732
- REVEL 0.71
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available