G31W (p.Gly31Trp) variant of TIGIT (Q495A1)
G31W (p.Gly31Trp) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G31W (p.Gly31Trp) variant details
- p.Gly31Trp
- ExAC rs776752435
- TOPMed rs776752435
- gnomAD rs776752435
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.29
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available