G31R (p.Gly31Arg) variant of TIGIT (Q495A1)
G31R (p.Gly31Arg) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G31R (p.Gly31Arg) variant details
- p.Gly31Arg
- ExAC rs776752435
- TOPMed rs776752435
- gnomAD rs776752435
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.15
- CADD 21.50
- PolyPhen-2 0.44
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available