G31E (p.Gly31Glu) variant of TIGIT (Q495A1)
G31E (p.Gly31Glu) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G31E (p.Gly31Glu) variant details
- p.Gly31Glu
- ExAC rs759559781
- gnomAD rs759559781
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.17
- CADD 22.20
- PolyPhen-2 0.81
- SIFT 0.07
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available