G25G (p.Gly25Gly) variant of TIGIT (Q495A1)
G25G (p.Gly25Gly) in TIGIT (Q495A1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
G25G (p.Gly25Gly) variant details
- p.Gly25Gly
- rs373334849
- gnomAD 3-114295558-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.428
- CADD 5.39
- Most common in the HGDP:SARDINIAN population (allele frequency 0.019)
- Structural context available
- Literature evidence available