G25D (p.Gly25Asp) variant of TIGIT (Q495A1)
G25D (p.Gly25Asp) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
G25D (p.Gly25Asp) variant details
- p.Gly25Asp
- TOPMed rs1169726816
- gnomAD rs1169726816
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.37
- CADD 21.90
- PolyPhen-2 0.97
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available