G12V (p.Gly12Val) variant of TIGIT (Q495A1)
G12V (p.Gly12Val) in TIGIT (Q495A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
G12V (p.Gly12Val) variant details
- p.Gly12Val
- gnomAD 3-114294096-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.04
- MetaLR 0.11
- MetaSVM -1.03
- CADD 22.40
- PolyPhen-2 0.10
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available